Birth Cohort

With an increasing interest in the influence of various biological and environmental factors on human development, the Birth Cohort was designed parallel to the PERSIAN Cohort, to further study this critical time of life. The overarching aim of the PERSIAN Birth Cohort is to study Developmental Origins of Health and Diseases (DOHaD) in the Iranian population. The study is conducted in the cities of Isfahan and Yazd, Rafsanjan, Semnan and Sari.

General objectives of the PERSIAN Birth Cohort are as followed:

  1. To investigate the relationship between genetic characteristics, reproductive factors, perinatal, socioeconomical, cultural, and environmental factors on human development, and eventually procedural living with disabilities during infancy, childhood and adulthood
  2. To explain the complex interaction between genetic factors and lifestyle with the social and natural environments
  3. To provide evidence for public health preventative measures


The main outcomes of interest in the PERSIAN Birth Cohort include:

  1. Pregnancy outcomes
  2. Child mental and physical health,
  3. Growth and development
  4. Early- and late-onset chronic non-communicable diseases